Christopher Nkunku hit a hat-trick for Enzo Maresca’s side.
Manchester City held off a late fightback from Watford to win 2-1, while Aston Villa were 2-1 winners at Wycombe.
Leicester avoided an upset as they got past League Two Walsall in a penalty shootout after the matched ended nil-nil.
Liverpool continue their trophy defence against West Ham at Anfield tonight, while Arsenal host Bolton.