Harlequins’ wing Cadan Murley will make his England rugby union debut in Saturday’s Six Nations opener against Ireland in Dublin.

Maro Itoje will captain England for the first time, having taken over from Jamie George.

Scrum-half Alex Mitchell’s recovered from a knee injury to start.

Fellow Quins player and former international scrum half, Danny Care, has told Jackie News he has high hopes for Michell.