The motorway will shut from Junction 10 at Wisley to Junction 11 at Chertsey from 9pm on Friday until 6am the following Monday.
National Highways says the last full closure on the 7th of March was much busier than ones last year and is urging drivers to plan ahead.
The £300 million project began in 2022 but “extreme weather” has pushed back the expected completion date to spring 2026.
