Police say the victim is thought to be in his 20s.
He was killed while standing in Shuttleworth Road near Battersea Park just before 10 o’clock.
Officers are searching for a suspect.
Detective Chief Inspector Neil John from the Met’s Specialist Crime Command who leads the investigation said:
“This is a tragic incident where a young man has lost his life whilst standing on a street in Battersea. Our thoughts are with his family and friends as they continue to struggle with this terrible news.
“Detectives are working at pace to gather as much information as possible and I would ask anyone who was in the area and saw events unfold, or anyone who has captured this on phone or doorbell footage, to contact police immediately.”
Detective Chief Superintendent Clair Kelland, from the South West BCU which covers Wandsworth, said:
“This murder will come as a terrible shock to the local community who will be waking up to this news.
“I want to reassure them that experienced homicide detectives from the Specialist Crime Command will be working tirelessly to find out who is responsible, and we will offer them all the support we can.
“There will be an enhanced police presence in the area over the coming days, and I would ask that the local community in Battersea speak with officers. Please tell us if you saw or heard anything, or wish to raise any concerns. I would also like to thank local residents for their co-operation whilst the crime scene is in place.”
At this early stage there have been no arrests and enquiries continue.
Anyone with information is asked to call police via 101 quoting reference CAD 8285/05Oct. To remain anonymous contact Crimestoppers on 0800 555 111.